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This chapter summarizes these recent findings that show how dynamic and controlled expression of multiple EBV genes can control the activation of B cells, entry into the cell cycle, the inhibition of apoptosis, and innate and adaptive immune responses.
In addition to MYC and TP53, CTNNB1 also may have potentially controlled expression of several genes that were more highly expressed in PAR vs. MFP.
Izard, J. et al. A synthetic growth switch based on controlled expression of RNA polymerase.
Controlled expression of the transgenes is required in many instances.
Schotta, G. & Reuter, G. Controlled expression of tagged proteins in Drosophila using a new modular P-element vector system.
Mechanistically, C/EBPβ bound the Nr4a1 promoter and controlled expression of this established monocyte survival factor.
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This allowed control of bacterial T4P expression and of adhesion through IPTG-controlled expression of PilC1 or PilC2 (Figure S1).
To probe the effect of copper-controlled expression of xyr1 on cellulase production, we constructed a recombinant strain expressing xyr1 under the control of P tcu1.
These carriers can induce apoptosis via hypoxia-controlled expression of a tumor suppressor protein p53 and a pro-apoptotic drug, Azurin.
Light-controlled expression of the glucagon-like peptide 1 was able to attenuate glycemic excursions in type II diabetic mice.
We used a mouse tumour model that allows tetracycline-controlled expression of ERBB2.
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