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The controllable biodegradability of bioactive glasses makes them advantageous over HA and related CaP.
CMCS is amphiprotic ether, derived from chitosan, exhibiting enhanced aqueous solubility, excellent biocompatibility, controllable biodegradability, osteogenesis ability and numerous other outstanding physicochemical and biological properties.
For the design of medical devices it is fundamental to use materials characterized by non-immunogenicity, biocompatibility, slow and/or controllable biodegradability, non-toxicity, and structural integrity.
Due to their excellent biocompatibility and controllable biodegradability, PLGA micro/nanoparticles could protect macromolecules from instant degradation in vivo while allowing tunable release rate and profile.
An ideal scaffold for tissue engineering should possess the characteristics of excellent biocompatibility, a suitable microstructure, controllable biodegradability, and good mechanical properties.
Polylactic-co-glycolic acid (PLGA) is currently the most used scaffold in tissue engineering, as it has good biocompatibility and controllable biodegradability.
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To formulate polymeric nanostructures, PLGA has attained noteworthy attention due to its controllable properties, complete biodegradability and biocompatibility, well defined formulation techniques and easy processing.
"If the plastic in question is biodegradable, its biodegradability will be identical," he said.
(Controlling the controllable, Jop Groeneweg 2002).
Moreover the product is biodegradable (>90% biodegradability).
PHB and PHBV have many advantages when compared to other chemically produced polymers like polyglycolate, polylactate, and poly(lactide-co-glycolide) which include excellent biocompatibility, biodegradability, easier processibility, and the controllable retarding properties which can be modulated by variations in processing and molecular weight of the polymer composition.
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