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Matching on hospital day of hypoglycemia provided a control time frame as well as controlled for variation in clinical status during hospitalization.
Such discrepancies may derive from different aspects of the study design (e.g., population, confounding control, time frame, and statistical analysis), and the U.S. EPA (2009) has called for further research.
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Determine a reasonable time frame.
All of these processes have to take place within a tightly controlled time frame, and each developmental stage has to be reached on schedule and in the correct sequence.
Co-culture of macrophage cells with La-IFN-β also resulted in rapid phosphorylation of STAT1 in a dose dependent manner, while no phosphorylation was observed in co-culture with the La-EV control in the time frame analyzed (Figure 2C).
Effect of intervention is greatest in the first 12 months with a significant increase in physical activity compared to control in this time frame.
Methodological problems such as retrospective design, lack of a control group, unspecified time frame, global assessment of effectiveness and side effects and lack of other assessment instruments than self-reports are inherent in effectiveness studies in a natural design such as used in the consumer reports [ 20].
"This level of immunity for presidential decrees is indeed unprecedented, but it is necessary and it is controlled by a time frame" that ends with the election of a new parliament, said Gehad el-Haddad, a senior Muslim Brotherhood adviser.
There was a trade-off between the number of matching criteria applied and the ability to identify suitable controls within the time frame.
In general, data showed evidence of ontogenetic phenotypic plasticity to defoliation in almost all traits measured; that is, the values for the defoliated series were statistically significantly different to the controls for the time frame of leaf area, shoot dry mass and LWR in the two ecotypes (Fig. 3).
"But no-one within the coalition doubts the need to get the deficit under control over a sensible time frame".
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