Under the same constraint, by comparing with dierent controls, the validity of the optimality of the obtained control is verified numerically.
Nevertheless, since V ˙ O 2 max. in such patients is, however, so much lower (25 46% of those in healthy controls), the validity of this comparison may be questioned.
However, such methods typically have no explicit control over the validity of the elements in the resulting mesh.
Reminded about the fact that BT and positive lymph nodes, as well as blood cultures, were also shown in animals belonging to the control group, the validity of the underlying porcine model must be judged carefully in studies concerning microbiological investigations.
The increase of malaria risk in the vicinity of swampy areas, which are preferred mosquito breeding sites, has already been documented and can be considered as an internal control of the validity of the analyses [13], [14], [16], [31].
In order to control for the validity of our results, therefore, we included in a second test only references from 2002 cited in papers published in 2003.
As an internal control for the validity of the analysis we examined expression of selected genes belonging to the heat shock regulon in samples of dnaC2 cells taken at 30°C and after 90 minutes at 38°C.
To control for the validity of the methylated DNA enrichment procedure, regions known to be enriched in DNA methylation (such as the H19 imprinting control region (ICR) or the intracisternal A-particle element (IAP)), or devoid of methylation (CSa) were profiled by real-time PCR (qPCR) prior to and following whole-genome amplification (WGA).
Their mRNAs were lower in ACTA1- Ctnnb1−/− muscles than control, indicating the validity of the method.
