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However, the notion that individual miRNAs usually control the expression of hundreds of different genes makes miRNA target identification highly complex.
Though miRNAs are only 18-22 nucleachdes, eacancontrolthel thexpressionof of hundreds of genes.
One miRNA can control the expression of hundreds of downstream gene targets, underscoring the importance of characterizing their functional roles in vitro and in vivo [ 25].
Thus, this suggests that the PRMTs studied here may regulate a common set of biological processes regulating directly or indirectly a few key major regulatory genes, which then control the expression of hundreds of genes associated with different biological responses.
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This transcription factor controls the expression of hundreds of target genes, many of which are also oncogenes or tumour suppressors, and have roles in cell proliferation and the cell cycle.
But because its cellular influence is vast (it controls the expression of thousands of genes and regulatory molecules), it's been tough for scientists to learn which of its many effects are cancer-causing.
Microarrays can measure the expression of thousands of genes to identify changes in expression between different biological states.
Such factors control the expression of DNA.
Kulasekara HD, Ventre I, Kulasekara BR, Lazdunski A, Filloux A, Lory S. A novel two-component system controls the expression of Pseudomonas aeruginosa fimbrial cup genes.
RNA molecules are uniquely capable of encoding and controlling the expression of genetic information, often as a consequence of their three-dimensional structures.
Thousands of human diseases could be treated by selectively controlling the expression of specific proteins in vivo.
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