Sentence examples for control the conformational from inspiring English sources
Wang and Oster proposed that interactions with the γ subunit would control the conformational and catalytic states of individual β subunits to sequentially generate torque.
The conformational changes experimentally observed in the enzymes by binding a broad range of ligands can be predicted by the most cooperative lowest frequency modes of motion by ANM, where the hinges are the key mechanistic regions of the structure that control the conformational ensemble.
In conclusion, we have shown structurally that ion binding and unbinding events in GltPh and, by analogy, in EAATs control the conformational state of the transporter, determining its competence to bind substrate and undergo transitions between the outward- and inward-facing states.
These findings confirm that the deleterious effects of the E715K mutation cannot be accounted for even by the complete loss of phosphorylation and therefore support the model that E715 controls the conformational properties of Ire1.
We sought to achieve redox control over the conformational equilibria between the closed and open state of the MBP domain.
Modeling and simulation results are presented for an initial set of bio-molecules that illustrates a procedure through which optical excitation can be used to control the molecular conformational state.
Its association with coregulatory proteins occurs through interactions with the surface of the ligand binding domain (LBD) and is controlled by the conformational changes induced by ligands ultimately modulating gene expression [ 95].
It recently has been proposed that the BH-HN undergoes conformational changes coupled to, and essential for, the nucleotide-addition cycle in transcription initiation and transcription elongation, and that the F-loop, and possibly the link region, control these conformational changes (Hein and Landick, 2010; Weinzierl, 2010; Kireeva et al., 2012; Nedialkov et al., 2013).
At any given temperature, these factors are responsible for controlling the different conformational states of the MB with respect to random coil, stem-loop and bound-to-target [21].
Mutational and biochemical analyses define the architecture of the ternary complex that recruits nucleotide-binding leucine-rich repeat receptors (NLRs) by manipulating the structural elements to control the ATPase-dependent conformational cycle of the chaperone.
