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Presentation speed of each control summary movie was set to match the duration of the corresponding highlight movies for the event boundary and event middle conditions (e.g., breakfast summary = 68 s, full movie = 328 s, summary movie presented at an increased speed of 450%).
The control summary report is generated by the BeadStudio software, which evaluates the performance of the built-in controls of the BeadChips across particular runs.
The Illumina BeadStudio software was used to view control summary reports, scatter plots of the total RNA control results from different days and scatter plots of daily run samples.
Control summary graphs generated by BeadStudio were used as quality assurance tools for hybridization, washing stringency, and background.
Complete conversion was confirmed using the internal bisulfite conversion controls in each pyrosequencing assay and the bisulfite conversion control summary graph for the Illumina GoldenGate panel.
To assess quality metrics of each run, several quality control procedures were implemented, including a total RNA control sample and assessment of control summary reports, which allows the user to look for variations in signal intensity, hybridization signal, background signal and the background-to-noise ratio for all samples analyzed.
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The genotyping method and quality control summaries are presented in Supplementary Material, Table S1.
Responsiveness of the IBD-Control summary scores measured by SRM was strong (table 6).
Hence, the ability to convert IBD-Control summary scores to an estimate of utility could support health economic evaluations.
All models confirmed the strong association between IBD-Control summary scores and disease activity indices, generic and disease-specific QoL and global assessment.
Conversely, negative correlations would be expected to exist between IBD-Control summary scores and traditional clinical measures of disease activity or severity.
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