Secondary outcomes address blood pressure control, glycemic control, renal function, and medication adherence.
We studied the number and function of vascular progenitor cells in 22 type 1 diabetic patients with history of microalbuminuria (MA+) and 22 type 1 diabetic patients without history of microalbuminuria (MA−), of similar age, diabetes duration, glycemic control, renal function, and no history of CVD.
We have demonstrated that, compared with those individuals not exposed to antidiabetic drugs, metformin use is associated with a lower mortality risk than other antidiabetic therapies even after adjustment for other potential prognostic factors including glycemic control, renal function, BMI, and blood pressure.
Major strengths of our study include the well-characterized, large population with type 2 diabetes with frequent BP monitoring and adjustments for control, renal function monitoring, the longitudinal follow-up for up to 7 years on study, the inclusion of a larger percentage of minorities than most studies of this type, and the hypothesis-driven direction of the current analyses.
We have additionally shown that these associations are independent of traditional risk factors for neuropathy, such as age, glycemic control, renal function, and smoking, and that SIF was a better indicator of neuropathy than cumulative glycemic exposure, as reflected by updated mean HbA1c.
We aimed to assess the glycaemic control of patients with T2DM and SHF treated with BB in a tertiary teaching hospital and the differential effects of a nonselective BB (carvedilol) versus a β1 selective BB (bisoprolol) on glycaemic control, renal function, albuminuria and lipid profile.
In contrast, prognostically relevant parameters deteriorated in controls: renal function declined slightly (creatinine) and sodium concentration decreased as well.
Using cutoffs similar to those used in the published literature, Regan Bailey (personal communication, 2011) found a prevalence (least-squared percentage ± SE) of 2.8 ± 0.2% for serum vitamin B-12 concentrations <148 pmol/L, 10.5 ± 0.4% for concentrations <198 pmol/L, and 25.6 ± 0.6% at <258 pmol/L in an NHANES sample of people aged ≥60 y with impaired but controlled renal function.
The concept of functionally specific renal sympathetic nerve fibers allows more finite control of renal function.
With conservative therapy of fluid control, her renal function recovered gradually.
Podocyte marker expression was correlated with albuminuria, glycemic control, and renal function.
