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The therapeutic goal now is to control progression of the disease.
Results suggest that maintenance of retroperitoneal adipocytes at appropriate diameters may control progression of metabolic syndrome symptoms such as glucose tolerance.
Endpoints need to reflect benefit to patients, and show that changes in tumour size either in absolute terms (response and progression) or relative to control (progression) are clinically relevant.
The study suggests that advancement of public health system could better control progression of non-communicable diseases among old people and thus promote successful ageing.
The coupling of cyclin dependent kinases (CDKs) to an intrinsically oscillating network of transcription factors has been proposed to control progression through the cell cycle in budding yeast, Saccharomyces cerevisiae.
Protein protein interactions also regulate enzymatic activity, control progression through the cell cycle, and allow the assembly of large protein complexes that carry out many closely related reactions with a common biological function.
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Post-operative chemoradiotherapy yields superior locoregional control, progression-free survival, and in some studies, overall survival compared to post-operative radiotherapy for high-risk patients in multiple randomized studies.
Primary endpoint is mucositis CTC°III, secondary endpoints are local control, progression-free survival, and toxicity.
This included local control, progression-free survival and loco-regional and distant failure.
Cumulative 3-year local control, progression-free survival, and overall survival were 91, 91, and 92%, respectively.
The parameters analyzed in the treated patients were local control, progression-free survival (PFS), overall survival (OS), and the treatment-related side-effects.
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