This is useful in terms of Good Manufacturing Practice protocol development and also important as it simplifies development of quality controls, potency assays [39] and decisions regarding release criteria.
It clearly indicates that IL-2 exposure and the temporal function of IL-2 during TCR stimulation control the potency of the CD8+ effector T cells generated.
Strikingly, these trajectories are indeed symmetrical in our experimental results, which is particularly surprising since we do not control the potency of the K5 and HY antigens for 5C.C7 and A(1)M clones.
Control standard potency was determined for each combination of lysate and standard with reference to the reference standard endotoxins EC5 or EC6 [U.S. Pharmacopoeia, Inc., Rockville, MD; 1 ng EC5 and EC6 = 10 endotoxin units (EU ] available at the time the assays were performed, by simultaneous assay of the control with the reference or with a control traceable to assay with the reference.
He said e-cigarettes posed several potential serious risks to public health, including lack of controls on potency, a means to discourage current smokers from quitting by providing an alternative in smoke-free spaces and the possibility "these products could serve as a pathway to nicotine addiction for children".
Results indicate that lipophilicity is an important factor controlling inhibitor potency.
It is likely that additional determinant(s) controls the potency of the late restriction activity following initial binding of a TRIM protein with HIV-1 Gag.
This indicates that major determinants controlling antifungal potency as well as morphogenicity reside within the γ-core motif of each defensin.
Finally, the parameter kmAtff, which controls the potency of CHOP activation by ATF4, affects all of the three states changing the basal and the active response levels and also the span of the intermediate state (Additional file 1: Figure S6(d)).
They are in control, their sexual potency a weapon to be wielded over hapless men.
