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An electrochemical immunosensor that mimics traditional ELISA type architecture has been constructed for the detection of antigliadin antibodies with control over the orientation and packing of gliadin antigen molecules on the surface of gold electrodes.
However, the adsorption of proteins is a complex process and often proceeds with a lack of control over the orientation and conformation of proteins at the surface.
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We also show how a micro-mirror array that allows full control over the orientations of its mirrors can be used to instantly change the field of view and resolution characteristics of the imaging system.
Further requirements to this self-organization are the homogeneous distribution of microtubule density and reliable control over the array orientation.
Synthetic platforms based on DNA origami enable excellent control over the spatial orientation and stoichiometry of the recruited proteins, allowing the assembly of protein cascades with increased pathway specificity and turnover rates13,18,19,20.
Very little control over the type, orientation and area packing density of the CNTs was evidenced with a largely qualitative analysis presented.
MACE is a cheap method which allows to achieve 3D morphologies strictly dependent on the surface metal patterning, thickness and distribution and guarantees a good control over the nanowires orientation with respect to the substrate [14].
Electrodeposition as a method of preparing thin nanoparticulate films has many advantages which include, among others, high purity of the electrodeposits, high yield, and good control over the size, orientation and distribution of particles across the conductive substrate [14, 15, 16].
Scaffolds are made of different biomaterials and manufactured using various techniques that, in some cases, do not allow full control over the size and orientation of the pores that characterize the scaffold microstructure.
Especially, template-based metal-assisted chemical etching [21 25] enables precise control over the diameter, length, orientation relative to substrate, packing manner, and cross-sectional shape of Si nanowires.
Since the bioorganic matrix has control over the size and orientation of CaPO4 crystals, the latter grow with a specific crystalline orientation the c-axes of the crystals are roughly parallel to the long axes of the collagen fibrils within which they are deposited (Palmer et al. 2008; Grynpas et al. 1993; Weiner and Wagner 1998; Currey 2002; Rho et al. 1998; Tzaphlidou 2008; Olszta et al. 2007).
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