However, these systems also face barriers, including limitations on data privacy, data sharing, business associates' agreements, and a lack of control over program modifications.
The previously reported selective nitration at tyrosine residues by use of copper electrodes in alkaline medium is not observed in the acid electrolysis system and shows the fine control over protein modification available by manipulation of electrosynthetic parameters.
2003: Besides Olaf Eliasson's more obvious futuristic allusion to the culminating effects human populations have on weather, and the denial and debate that feasibly can one day escalate into warfare over which populations have control over weather modification, is the ancient root of politics that makes it akin to religion.
Selectivity and spatio-temporal control over the modification can sometimes be attributed to signalling cascades resulting in the phosphorylation of the E3 or the substrate, but more often the dynamic regulation of sumoylation is poorly understood (Guo et al, 2007).
It is concluded that IR fs irradiation provides a high degree of control over the induced modifications, a feature of interest in the design of new laser restoration schemes.
To reduce the expenditure of hazardous organic solvents and enhance control over the chemical modification, solvent-free techniques have emerged as a dominant trend in the field of surface engineering research (Desmet et al. 2009).
A roadblock to translation of (virus-based) nanomaterials into commercial products is the lack of control over synthesis and modification conditions at larger volumes and scales.
The environment of the Ag+ in solution in many cases can be critically important for the rational control over surface and interfacial modifications of the molecular absorption process.
Exact control over sequence composition and modification is an important requirement for the intentional design of structure and function.
Additionally, conjugates containing a protease-cleavable linker at one of two sites exhibited different plasma stabilities, demonstrating that control over the site of modification is important in tuning the pharmacokinetic parameters of ADCs.
However, important questions remain, which require further, more detailed mechanistic study, regarding whether and how these two, or additional, post-translational modifications regulatep53 control over cell fate through modulating its cytoplasmic localization and/or its cytoplasmic pro-apoptotic activity.
