Loss of TP53-mediated control over ETS1 dependent transactivation of IKKα may represent a novel pathway for the constitutive activation of NF-κB mediated gene expression and therapy resistance in cancer cells [ 28] TP53 is therefore an ETS1 and ETS2 target gene [ 29].
How to cite this article: Garrigues, A. R. et al. Electrostatic control over temperature-dependent tunnelling across a single-molecule junction.
We show that photo-cleavable gal4-MOs enable temporal control over gal4-dependent effector genes, here GFP, providing the potential for temporal control and cell-type specificity in many existing Gal4-UAS transgenic lines (Scott et al., 2007).
Au NPs have been most intensively investigated for imaging applications over the last few decades; well-established methods of Au NP synthesis and surface modifications have allowed for control over their morphology-dependent optical properties [7 13].
Experimental evidence indicates that posttranslational control over extrinsic, DISC-dependent caspase-8 activation encompasses glycosylation, nitrosylation, ubiquitylation, and phosphorylation, and that these modifications can be physiologically and pathophysiologically relevant.
It is suggested that executive control over semantic processing is dependent on a distributed neural network that includes bilateral dorsolateral prefrontal cortex, the left angular gyrus and left posterior temporal cortex (Thompson-Schill et al., 1997; Wagner et al., 2001; Whitney et al., 2011, 2012; Noonan et al., 2013).
Finding the right balance between activating many types of adaptive responses and maintaining tight control over gene expression both factors dependent on the level of transcriptional deregulation is the key for maximizing adaptability to environmental influences while minimizing the threat of malignant transformation or other pathologies.
"Being dependent on public release of information on radiation hazards (or evacuation orders) that we have little control over is a different thing entirely".
The strain energy density (SED) averaged over a material dependent control volume proved to control fracture and fatigue behaviour of different materials in many engineering problems.
The technique allowed for homogenous distribution of cells and micropores within the scaffold, increasing the absorption coefficient of large solutes (70 kDa dextran) over controls in a concentration-dependent manner.
