It could be noted that control of the strength of the implicit feedback loop through adjustment of the sequestration strength is a robust property of a MAPK cascade such as M4, as both M4K1 and M4K2 (simulated with different sets of parameters) exhibited similar relation between sequestration strength and the strength of the implicit negative feedback loop.
Finally, a conceptual design for the on-line control of sinter strength was even proposed based on the present results.
We previously reported a dismantlable adhesive system using degradable polyperoxides as curable and pressure-sensitive adhesives and the control of bonding strength by the radical chain degradation of the polyperoxide adhesives [16 18].
Through specific binding to ADAM22, LGI1 was shown to participate in the control of synaptic strength at excitatory synapses, whose malfunction may result in epilepsy [14].
This became stronger as the toxin concentration was increased; therefore, dose-dependent control of the strength of ablation might be possible (Additional file 1: Figure S2).
Modulation of an interaction by modification of multiple residues even allows for rheostatic control of binding strength, where the affinity for an interaction partner is gradually altered by multiple modifications that additively enhance or diminish the interaction.
These data suggest that the RBS Calculator is useful for designing RBS parts in PCC 7002; however, as shown in a recent paper by Li et al., fine control of RBS strength may not be possible with this prediction program.
It was concluded that the position of functionally graded layer is the controlling factor of strength of FGG specimens.
Specifically, we placed all three reporters under the control of a medium strength RBS (BBa_B0032) and four different promoters of variable strength (in order of decreasing strength BBa_J23119, 101, 106, 115) on a low-copy vector (BBa_PSB4A5).
This is due to firm control of costs, the strength of easyJet's network, tight capacity discipline and pricing actions taken in the second half of last financial year".
