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Determination of low levels of drugs is an important issue in quality control of pharmaceuticals.
Naphazoline hydrochloride with stated purify of 99.2% (lot No.100111-201104) was purchased from the National Institute for the Control of Pharmaceuticals and Biological products, Beijing, China.
Recent studies highlighted the interest of SFC for the quality control of pharmaceuticals, especially in the case of the determination of the active pharmaceutical ingredient (API).
In recent years, more strict regulation related to the quality control of pharmaceuticals led to increasing demands on automation of the analytical assays carried out in appropriate control laboratories.
Diphenyl (purity ≥99%, internal standard) was purchased from the National Institute for the Control of Pharmaceuticals and Biological Products (Chengdu, China).
Among the analytical techniques currently used for the purity control of pharmaceuticals, electrokinetic chromatography (EKC), a mode of capillary electrophoresis (CE), was shown to be a powerful tool in the field of chiral separations [ 7– 17].
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Das et al. (2012) studied the control of pharmaceutical effluent parameters through bioremediation.
Standard reference isoimperatorin and bergapten (purity >98%%) were purchased from National Institute for the Control of Pharmaceutical and Biological Products (Beijing, China).
Six reference compounds were purchased from the National Institute for the Control of Pharmaceutical and Biological Products, China.
Columbianadin and bergapten (IS) were purchased from National Institute of the Control of Pharmaceutical and Biological Products (Beijing, China).
TF-1 cell line was obtained from the Chinese Institution for the Control of Pharmaceutical and Biological Products (Tiantan Xi Li, Beijing, China).
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