Sentence examples for control of lineage from inspiring English sources

We present data showing that the control of lineage specific expression of IRF-8 is confined to an intronic segment.

Moreover, this study reveals that in addition to positional information and asymmetric cell divisions, cell shape plays an important role for the control of lineage divergence during mouse preimplantation development.

Entry into lineage-specific differentiation from the pluripotent state is pivotal to mammalian development, yet the molecular mechanisms behind control of lineage commitment remain poorly understood.

Our data reveal a crucial function of HDAC1/HDAC2 in the control of lineage specificity and a novel role of HDAC1 as a tumour suppressor in the epidermis.

SWI/SNF complex was a multi-subunit chromatin-remodelling complex which mobilizes nucleosomes and remodel chromatin, playing key roles in control of lineage specification, gene expression and repression, metastasis, epigenetic tumor suppression.

However, our results show that repression of Igf1 expression by Ezh2 in lung epithelial cells is likely to be a crucial process for maintaining a proper control of lineage specification during embryonic lung morphogenesis.

Gene duplication and diversification may allow better control of lineage-specific pathogens.

This indicates that the double-positive keratin staining pattern in vitro is more likely to reflect a specific progenitor state than a loss of control of lineage-specific gene expression.

We explored evolutionary conservation of regulatory elements and natural human inter-individual epigenetic variation in Treg cells to identify the core transcriptional control program of lineage specification.

Experiments and mathematical modeling implicate feedback control of cell lineage progression, but a broad understanding of what lineage feedback accomplishes is lacking.

Further characterization of these context-specific REST and CoREST transcriptional submodules and their regulatory topologies is necessary not only for understanding the control of glial lineage elaboration but also for defining the emergent properties of REST and CoREST networks and their dynamic functions, including potential roles in disease pathogenesis.