Sentence examples for control of hilD expression from inspiring English sources
Nevertheless, neither RfrA nor RfrB mediates Fur control of hilD expression [23].
Nevertheless, the previously described Fur·Fe2+-mediated activation of hilD expression remains unknown [23], [31].
Direct regulation by Fur of hilD expression would allow rapid signal transduction once the Fe2+ concentration increases, situating PhilD in a similar hierarchic position as sRNAs that indirectly control other genes positively regulated by Fur.
For example, it is well known that osmolarity and bile salt concentration influence T3SS production by controlling hilD expression through the EnvZ/OmpR and BarA/SirA two-component systems, respectively [16] [18].
It is therefore likely that Fur·Mn2+ acts as a transcriptional activator of S. enterica hilD expression.
In vivo and in vitro experiments revealed that Fur bound to the upstream element of PhilD activated hilD expression, but did not activate transcription from PhilD*.
Also, the presence of the KanR cassette upstream of BoxA did not modify hilD expression, since the transcription level of this gene was similar to that obtained using the SV5015 wild-type strain (Figure 5).
Thus, nucleoprotein assembly along the promoter region may interfere with, rather than stimulate, the interaction of RNAP with PhilD, returning hilD expression to its basal level.
