This may be improved by temporal control of expression to ensure NatB is both expressed and functional before the target protein is expressed.
These results show that S. typhimurium can express and secrete a functional TRAIL protein, with control of expression by genotoxic damage from a small dose of radiation.
Here, we demonstrate optimal rebalancing of the intracellular redox state by model-driven control of expression using n-butanol production in Escherichia coli as a model system.
Reliably manipulating such networks would be valuable for many applications in biotechnology; for example, in having genes turn on only under a defined set of conditions or implementing dynamic or temporal control of expression.
Optogenetic control of CREB function was characterized in vitro, in HEK293T cells, and in neurons where blue light enabled control of expression of the CREB targets NR4A2 and c-Fos.
A marionette's arms are manipulated by strings, but Henson used rods to move his Muppets' arms, allowing greater control of expression.
The heat shock protein 70 (hspromotermoter allowed for temporal control of expression of Gal4.
Moreover, AP-1 transcription factors along with Ets proteins can exert a combinatorial control of expression of several genes that include importantly metalloproteinases.
Control of expression of VAChT and ChAT is poorly understood, and distinct cholinergic neurons show different requirements for regulatory regions within the cholinergic gene locus [19] [22].
The control of expression in dinoflagellates is also enigmatic, with studies showing mRNA quantity does not reflect protein levels even in strongly circadian genes such as luciferase [12].
This type of control of expression, which can involve altered mRNA stability, has been reported for other H. pylori genes [51], [52], [53].
