Further studies are required to define whether KCNE1 and KCNE3 determine membrane surface expression of Kv12.2 through control of export to the plasma membrane, promotion of endocytic recycling, or a combination of both mechanisms.
More recently, a second model for quality control of exported proteins has been suggested involving mediation by the chaperone complex 14-3-3 14-3-3 14-3-3l. 2002; Yuan et al. 2003).
The Chinese have their pet issues as well: Beijing is pushing Washington to loosen controls on exports of high-technology equipment with potential military applications.
They gained control of aluminum exports at a. time when aluminum cost $2,000/ton on world markets but could be bought.
This variation between neuronal populations might be explained by variability in control of nuclear export of repeat RNA species; in this context, it is interesting that mutations in hGle1, a mRNA export adaptor, have recently been shown to cause selective death of motor neurons [ 14].
Later, looms were set up to weave silk, but China retained control of sericulture, exporting only silk thread or fabric, both of which were expensive.
PCTAIRE kinases bind 14-3-3 14-3-3 14-3-3deczek et al. 1997), which have themselves been improteins in the control of ER export.
There are several mechanisms to control glycerol accumulation: regulation of gene expression, metabolic adjustment, and control of glycerol export and import (Hohmann 2002b).
The lumen of the ER (endoplasmic reticulum) is the subcellular compartment responsible for folding and quality control of proteins exported to the cell surface or extracellular spaces.
However, the adaptor protein Gle1, that plays an important role in the control of mRNA export in yeast [ 62], appears to be missing from Amoebozoa, Plantae, Chromalveolata, and Excavata, suggesting it is an innovation specific to Opisthokonta.
