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In patients with recent-onset active RA, a tight control of disease activity with TNF blockers, as implemented in the GUEPARD trial, allowed more patients to achieve remission without disability and radiographic progression than the routine care administered to the patients in the ESPOIR cohort.
In patients with recent onset active rheumatoid arthritis, a tight control of disease activity allows more patients to achieve remission without disability and radiographic progression.
There is a clear need for prevention studies (lipid and blood pressure control) in conjunction with control of disease activity, which requires delineation of the factors that drive vasculitis and endothelial cell activation.
Hence, the need for new drugs and therapeutic strategies aiming at minimizing damage accrual through a better control of disease activity and a steroid-sparing potential is paramount.
Targeting maspin for control of disease activity and cancer prophylaxis may be a promising novel therapeutic strategy for IBD.
Effective control of disease activity decreases mortality.
Control of disease activity is usually achieved within several weeks.
Despite advances in therapies, the control of disease activity in SLE remains suboptimal.
Canakinumab led to a sustained control of disease activity even after secondary failure of anakinra therapy.
This may reflect suboptimal control of disease activity or decrease in TNF-dependent NO production.
However, some patients experience worsening structural joint damage despite apparently good control of disease activity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com