Exact(5)
Efforts to control morbidity of the disease are being stepped up worldwide and elimination is now an aim following the 2012 WHA Resolution 65.21 which advocates elimination of schistosomiasis in some countries [ 4, 5].
Anderson 1991 suggests that, in order to control morbidity in areas of endemic infection, targeted treatment should be repeated every three to four months for roundworm and whipworm, with longer intervals acceptable for longer-lived species such as hookworm.
However, our data indicate that the POC-CCA could be a useful tool in medium-to-high prevalence areas that are presently working to control morbidity from S. mansoni infection, the first step of which is to do prevalence mapping to determine where and to what degree PCT should be implemented.
Whilst immense efforts are being made to control morbidity due to helminthiasis and the big three diseases with special emphasis on regular combined school based treatment of primary school children [ 3], it should be borne in mind that community perceptions, knowledge and practices have a major role in sustainable control interventions.
36 In the light of our findings, long-term controlled intervention studies are needed to show whether MPA or VPA as the main component of intervention programmes has a better benefit risk balance for obese individuals in terms of adherence, weight control, morbidity and mortality.
Similar(55)
We examine the effects in controlling morbidity and mortality as well as impact on malaria transmission, thus bridging a gap between field trials of efficacy and malaria transmission models.
The current mainstay for schistosomiasis control is to mitigate against the burden of the disease by controlling morbidity through chemotherapy with praziquantel (PZQ).
In areas where schistosomiasis is highly endemic therefore, the present goal is to mitigate the burden of the disease by controlling morbidity (Fenwick and Webster 2006).
Despite it being considered for decades that the adaptive immune response is the most important protective mechanism during chronic infection, recent studies have suggested the importance of the innate response as a regulatory mechanism for controlling morbidity during disease.
The primary endpoints of these clinical trials are survival, long-term regional control, and morbidity.
An efficacious vaccine is needed to control the morbidity and burden of rising healthcare costs associated with genital Chlamydia trachomatis infection.
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