Your English writing platform
Discover LudwigSuggestions(1)
Exact(3)
24 h LVP-treated DC matured with LPS are able to stimulate IL-2 secretion by allogeneic T cells similarly to control mDC.
In contrast, wild-type and 3xTg-AD mice immunized with control MDC construct fused with an irrelevant tumor antigen [30] did not produce anti-Aβ antibody (Figure 2A, 3A).
Levels of TNF-α and IL-6 were increased by a factor of > 178 for TNF-α and a factor of > 36 for IL-6 when immature DC were co-cultured with H-1PV-induced SK29-Mel-1 cell lysates compared with control (mDC).
Similar(57)
We observed that CD83 was significantly elevated both in MDCs (median 1.8%) and PDCs (median 2.8%) in patients with PDAC compared to control MDCs (median 0%) and PDCs (median 0%) (Figure 2A).
We also measured the level of CD40, i.e. a costimulatory molecule important for the activation and survival of DCs and found significantly increased levels of CD40 on MDCs and PDCs both before (median 432; median 584) and after tumor resection (median 524, median 656), compared to those expressed on control MDCs (median 322) and PDCs (median 349) (Figure 2B).
As a control, mDCs from HVs were incubated with autologous T lymphocytes.
pDC and mDC were sequentially purified by magnetic cell sorting (MACS) using anti-neuropilin-conjugated magnetic microbeads (pDC) and biotin-conjugated anti-CD1c followed by positive selection using anti-biotin-conjugated magnetic microbeads (mDC), from RA PB (n = 3) and SF (n = 3) and compared with normal healthy controls (mDC, n = 4; pDC, n = 5).
As with normal control mature mDCs, SLE mature mDCs induced higher T-cell proliferation than did immature mDCs.
SLE mature mDCs tended to induce lower levels of T-cell proliferation when compared with control mature mDCs.
For control purposes, mDCs were also incubated with GM-CSF alone or the irrelevant TLR agonist CpG ODN 2216 (mDCs do not express TLR9), and pDCs were also incubated with IL-3 alone or with control ODN 2216c.
Neither SLE nor control BM mDCs produced detectable IFN-α.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com