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CGG repeat numbers were determined by comparison with a control individual of 52 CGG repeats.
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Treated and control individuals of both species were maintained in a temperature-controlled chamber at a constant 20 ± 1.5 °C after treatment.
612 unrelated control individuals of German origin served as controls for case-control analysis to investigate the role of variants in CFH, C3 and ARMS2 for AMD susceptibility.
Selected type 2 diabetes associated genetic variants were genotyped in 1,165 type 2 diabetic patients and 1,136 normoglycemic control individuals of Southern Han Chinese ancestry.
To further examine the frequency of mutations in TARDBP in sporadic ALS, 279 ALS cases and 806 neurologically normal control individuals of European descent were screened for sequence variants, copy number variants, genetic and haplotype association with disease.
The dataset consisted of 2760 T2D cases and control individuals of Northern European descent.
Furthermore, the missense changes had not been found in 140 control individuals of comparable ethnicity.
They were analyzed in 1,651 patients with RA and 1,619 control individuals of Spanish ancestry.
Tests were administered according to standard procedures and interpreted by comparison with control individuals of similar age and education.
Additionally, these three mutations were not detected in 500 unaffected control individuals of matched geographical ancestry, as examined by Sanger sequencing.
Mutations in Turkish, Kosovan, Iranian, and both Gaza families were excluded in 112 DNAs from Jordanian control individuals, whereas mutations in the Guatemalan and Scottish families were excluded in 96 DNAs from control individuals of European descent.
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