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The expected control incidence was calculated based on historical incidences weighted to account for patients with previous rituximab treatment.
This finding also suggests that conclusions from studies where the "control" incidence of acquired BSI is higher than this may not be directly transferable to all ICUs.
This locus was shown to control incidence of acute EAE in male mice, with a dominant effect of RIIIS/J alleles on protection from disease development.
Interval cases, expressed as a proportion of the control incidence, increased from 12% in the first year to 67% in the third year.
Mosaic individuals show an increased cancer risk and recurrent anomalies affect important genes known to control incidence of hematopoietic cancers, such as TET2 and DNMT3a (Jacobs et al., 2012; Laurie et al., 2012).
The effectiveness of POE-POP to control incidence and severity of diarrheal disease was expressed as the sum of DSS and was found to be much lower (for 90.74%) in the treated than in the control pigs (5 vs. 54).
Similar(53)
The NCI "DevCan" program was used to calculate cumulative control incidences for cancers affecting Fanconi anemia patients.
The observed lack of difference in reported control incidences across groups lends support to our approach of basing comparative analyses on concurrent controls.
External control incidences were calculated based on integrated data from the rituximab RA clinical development program that used pooled data of all patients exposed to rituximab (all-exposure population).
For the selection of controls, incidence density sampling was used, thereby matching the controls on time [ 19].
Over the entire 8-year period, the annual frequencies of medical visits related to keratitis were significantly higher in cases compared with controls (incidence rate ratio of cases vs controls=5.46, 95% CI 3.13 to 9.53).
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