While most women won't experience clinical depression or need antidepressant medication soon after starting birth control, experts say the results suggest that doctors who prescribe birth control to first-time users should be on the lookout for potential changes in mood in the first few months.
In order to control for potential systemic changes in BMD, data were also analysed using the contralateral overall hip BMD as a covariate both by using analysis of covariance (ANCOVA) and also by assigning the value in each of the peri-prosthetic regions of interest at each given time point as its percentage difference from the contralateral side.
To control for potential tissue culture induced changes, triplicate cultures were plated and incubated for the same length of time as the treated cultures, with no change in morphology or expression.
To control for potential artifacts resulting from changes to the cellular environment upon salt stress on ABACUS1 (e.g., by increased solute concentrations), we also measured DxAm/DxDm ratios in ABACUS1-80µ and ABACUS1-nr leaves 24 hr after transfer to osmotic stress, ABA and controleavestions.
By using population-based matched controls, we were able to control for potential confounding introduced by a possible change in the proportion of females among patients with multiple sclerosis throughout the 1900s and sampling and/or recall bias that might be present in a clinic-based study.
Although our regression equation includes controls for a broad set of individual and household characteristics, this may not be enough to control for potential differences in group-specific compositional changes over time.
However, to control for potential confounding effects, treatment utilisation as well as changes in the dose of antidepressant medication will be closely monitored during the study period.
Including a wide range of potential confounders in the study design also ensured to control for potential indirect effects of trade on our outcome variable through changes in these sectors.
We were unable to control for potential confounders like physical activity, psychosocial factors and other environmental factors that may have caused changes in health behaviour.
