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Although this method has certain advantages from a policy perspective, it precludes adequate control for case mix.
Future investigations might control for case mix and time trends, employ suitable comparison groups, and consider other analytic approaches for analyzing time series data such as interrupted time series data, or ARIMA methods [ 44].
For other areas of healthcare, determining the level of granularity most relevant for interpreting differences and what metric is to be used to control for case complexity are key decisions to be collaboratively made at the outset.
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We started analysing and discussing eight consultations in this manner, as this number is mentioned to control for case-specific aspects in communication assessment [ 13, 31].
One might argue over the rigor with which one can satisfactorily control for case-mix differences, but we generally concur with the authors' findings.
After control for case-control status and established liver cancer risk factors, coffee intake was positively associated with C-peptide and inversely with IL-6, GLDH, ALT, AST, GGT, alkaline phosphatase, total bilirubin, and AFP.
The variables available to control for case-mix in our analyses (a subset of the variables included in previous studies) included gender, presence of any congenital anomaly, race, gestational age, and birth weight <10th percentile for gestational age.
Although vignettes are suitable for comparative analyses because they control for case-mix, further studies are needed to confirm that the results from vignette-based questionnaires are in fact a valid measure of the real-life clinical care provided by anesthesiologists.
A person could be selected multiple times as a control for cases in different calendar years.
Despite many efforts, no study has ever definitively documented greater mortality in July after controlling for case mix and severity.
Much of the research on ancillary service utilization is limited by inadequate controls for case mix severity and other demand factors.
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