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2. Examined the relationship between the age-associated protein deposit and the previously described quality control "foci" (Q-bodies, JUNQ, IPOD and INQ).
Nevertheless, numerous studies have reported the localization of chaperones to cytoplasmic quality control foci upon exposure to proteotoxic stresses (Aguilaniu et al., 2003; Erjavec et al., 2007; Kaganovich et al., 2008; Specht et al., 2011; Wolfe et al., 2013), and GdnHCl blocks the association of Hsp104 with at least one substrate (Winkler et al., 2012).
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