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Blinding is not possible for the HARMONY Study due to the wait-list control design of the study.
Because of the case control design of the study, the results can not infer a causal relationship.
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Moreover, the case-control design of the study means that including them would overrepresent the prevalence in the general population.
Finally, the case-control design of the study limits our ability to infer causality or the direction of effects between presumed exposures and outcomes.
A second limitation is the fact that the nested case-control design of the study may overestimate the true predictive capacity of the models because of the relative high event rate in case-control studies (27).
Both the case-control design of the study and the fact that the relationship between use of rice straw as cooking fuels and development of young adult cataract was not consistently significant in comparisons with the two controls, preclude our drawing firm conclusions regarding a causal relationship between the cooking with rice straw and the risk of developing young adult cataract.
PG, AT and ER provided substantial contributions to the enrolment of cases and controls, design of the study, definition of the objectives; they revised the paper critically for important intellectual content.
Based on the transient modeling developed in the previous paper, the control design of the air-cooled chiller is studied.
Figure 16 shows a flowchart for calculating the maximum allowable spacing of the flexural reinforcement (smax) for the crack control design of the PSC members proposed in this study.
The case-control design of this study and the size of the sample (n = 1022), with complete data, allowed us to carry out a differentiated statistical analysis.
However, the case-control design of the current study offered the opportunity to examine specifically the question whether the TF gene SNP rs3811647 on Chr.
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