This change in expression potentially provides a novel androgen-independent biomarker and manipulation of its activity or its expression may provide therapeutic possibilities and insights into contributory aspects of the complex molecular pathology of prostate cancer.
While such a continuum is controlled by progressive subsidence, specific collapse geometries result from secondary contributory factors (roof aspect ratio, collapse symmetry, pre-existing faults).
This method is aimed at ITS – as was VRUITS − and is comprehensive in its approach, covering all three dimensions of road safety − exposure, crash risk and consequence, the effects due to behavioural adaptation in addition to the engineering effect (effect on target accident contributory factors) and is compatible with the other aspects of state-of-the-art road safety theories.
Consequently, the inclusion of numerous different aspects of control within the constructs could be a major contributory factor to the low correlation.
The possibility that each indicator provides the same contributory power requires replication with other samples, however researchers may find reassurance that each aspect of the formal clinical examination is important for understanding the associations of obvious caries experience with other psycho-social and demographic factors.
The strength of this study lies in the broad range of health outcomes measured including frailty, an important indicator in older populations, the detailed lifestyle information, the use of self rated socioeconomic position to take into account the psychological aspects, and the use of primary data which allows the linkage of contributory factors to health outcomes at the individual level.
One study reported 26 deaths and felt that MEs were a contributory factor [ 31].> The determination of factors contributing to MEs is an important aspect of this review because preventing MEs from reaching the patient depends on a sound knowledge of the causes or contributing factors.
It appears that the combination of different aspects of health and social care of the multi-agency clinic (one-stop shop) was contributory to the success of the clients in reducing drug use and stabilising lifestyles, as reported by the interviewees.
Although the qualifications and workplace settings of personnel in early childhood centres are recognized as perhaps the most significant contributory factor towards achieving and maintaining high quality services, there is little research which has looked systematically at this aspect of early childhood provision across Europe.
See also contributory negligence.
