Sentence examples for contributor to pain from inspiring English sources

Whereas a key role of the central nucleus of the amygdala (CE) has been established in integration of nociceptive information, the concept of the lateral nucleus of the amygdala (LA) as an important contributor to pain and its emotional component is still emerging.

NCT01697241 Osteoarthritis (OA) is the most common joint disease and a major contributor to pain, decreased physical function and decline in health-related quality of life [ 1].

ClinicalTrials NCT01039337 Osteoarthritis (OA) of the hip is a major contributor to pain, decreased physical function and decline in health related quality of life (QoL) [ 1].

Needless to say, the study does not consider several other potentially relevant risk factors, including inflammatory disease, fracture or the psychological component in back pain, which is an important contributor to pain and disability.

Although the global prevalence of RA itself is modest (0.24%), the disease is severe and protracted and is therefore a major contributor to pain and disability accounting for approximately 5 million disability-adjusted life years (DALYs) in 2010 [ 18].

Since then, substance P receptor antagonists have failed as analgesics in a number of clinical trials, and it is now widely recognized that of all the neuropeptides released by C-fibres, CGRP is a more likely potential contributor to pain pathophysiology, particularly in migraine.

To determine comorbidities that cause pain and the potential contributors to pain in individuals with chronic obstructive pulmonary disease (COPD).

Others got structural massage, which aims to identify specific musculoskeletal contributors to pain and to release restrictions on muscles causing the distress.

Clinical Trial Registration Number: NCT01435109 Knee and hip osteoarthritis (OA) are among the most common chronic health conditions and leading contributors to pain and disability among adults [ 1– 6].

However, unresolved inflammation can often lead to neuroinflammation that can occur in the CNS and peripheral nervous system (PNS), characterized by the activation of glial cells (e.g., microglia, astrocytes, and satellite glia), which are key contributors to pain exacerbation.

Given these observations and the lack of association between Sharp scores, CRP, swollen-joint count, tender-joint count, and high MDHAQ pain scores, we believe that the associations between patient global assessment/MDHAQ function and MDHAQ pain may be attributed to non-RA-related factors, and that the likelihood that inflammation and joint damage are major contributors to pain is low.