Whereas several electrophysiological parameters for some of the mutant channels have been reported by other groups, little or no information was available on the contribution of possible maturation/trafficking defects to losses-of-function for the mutants.
This finding might imply that cancer patients' ability to interpret the contribution from pain to loss of function is limited.
A previous study in the cultured Drosophila hemocyte S2 cell line also identified ept as a negative regulator of Jak-Stat signaling [46], but the extent to which this relationship is conserved in developing tissues in the whole organism and its contribution to ept loss-of-function phenotypes were not addressed.
To understand the mechanism of apoptosis and evaluate its contribution to the loss of layer II/III neurons in Nde1 mutant brains, we examined its associated cellular processes and found that the apoptosis in both Nde1−/−Lis1+/− and Nde1−/− mutants corresponded with increased DNA damage.
The court of George I believes that a large contribution to the loss of the White House was the perception that the president was a wimp.
These results suggest that the defective synthesis of mature sororin protein makes a major contribution to the loss of sister chromatid cohesion in cells lacking spliceosome subunits (Fig 8B).
For example, if a shipper's cargo is voluntarily jettisoned in a storm in order to save the vessel from total loss, the general average clause requires the insurers of the hull and of all other cargo interests to make a contribution to the loss of the shipper whose goods were sacrificed.
Therefore the primary blackbody radiation contribution to the loss of trapped atoms at room temperature in Fig. 23(a) is direct blackbody photoionisation.
An experiment was carried out to identify the cause of, and quantify contributions to, seed loss from two different designs of header fitted to the combine harvester; a standard header and a header with a conveyor fitted behind the cutterbar, claimed to assist crop flow into the auger.
The framework rests upon the simulation of full cell voltage profiles from the superposition of equivalent, artificially degraded half-cell profiles and allows to separate aging contributions from loss of available lithium and active materials in both electrodes.
Based upon the butterfly being a kind of poikilothermal animal, it could be inferred that lower reflectance made contributions to reducing the loss of solar energy so that the butterfly could maintain body temperature, which confirmed that the black areas possess a better light trapping property.
