We used linear modeling to find that mutation (as exemplified by the mutational ENC) greatly contributes to ENC variability, incorporating the contribution of the Position and Strand predictors.
We utilized, as a routine, the loess normalization procedure, which does not take into consideration the tip-to-tip variability because, under the present experimental conditions, the ANOVA showed that the contribution of the position on the array to the total variability were negligible.
The putative contribution of the positions 5 and 186 to functional divergence between subfamilies was unachievable because of the high levels of divergence in the C- and N-terminal parts of the NCS proteins.
Therefore, under the hypothesis that there is an underlying dynamics (i.e., fluctuation profile) for the three-dimensional (3-D) structure of a protein, which is crucial for the function, our metric dfi quantifies the contribution of each position to this functional dynamics and is designed to capture the key residues mediating the function through the residue interaction dynamics.
The authors concluded that the potential contribution of body position in elevating IAP should be considered in patients with moderate to severe IAH or ACS.
The contribution of genomic position of orthologs to the result of multidimensional clustering (fig. 4) was checked by linear multiple regression analysis using the lm function of the R program.
A combinatorial library of a relatively simple designer-cellulosome system composed of three enzymes was prepared using a synthetic biology approach for examining the contribution of enzyme position, CBM location and intermodular linker length to cellulose-degrading activity.
However, traditional accounts of the health impact of ordered differences in SES (e.g., by occupational prestige or income) have not clearly disentangled the contribution of social position from access to material resources (Kawachi, Adler, & Dow, 2010; Marmot & Wilkinson, 2001).
Fourth, using a modified yeast two-hybrid assay to reflect quantitative differences in protein protein interactions while mutating amino acid 46, we determined the contribution of NDUFC2 position 46 to mitonuclear protein protein interactions.
