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Relative contribution of proliferation and apoptosis of target genes in two-dimensional culture.
We (ii) investigated the contribution of proliferation and migration towards the resulting wound fill by the remedy (0712 2).
The contribution of proliferation genes to the transcriptional programme of pimonidazole-positive tumours (Table 1) suggested increased proliferation activity.
However, the cellular origin and respective contribution of proliferation vs. infiltration remain elusive following skeletal muscle injury.
In vivo BrdU incorporation experiments suggest that the contribution of proliferation to the effect of Ro3303544 in vivo is not significant.
Of note, without prior MMC treatment, the migration index is greater), highlighting the nonnegligible contribution of proliferation to "apparent" chemotaxis occurring with longer assay times.
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The Spearman's correlation between the risk scores produced by the predictor and that produced by GGI, previously described in Sotiriou et al, 2006 [ 5], was calculated to assess the contribution of proliferation-related genes to the prognostic ability of the current predictor.
Additional file 9: Figure S5 Relative contributions of proliferation and apoptosis of target genes in two-dimensional culture is unchanged by the presence of feeder cells.
The absence of serum was beneficial for subsequent experiments evaluating migration and invasion, because contributions of proliferation to the results observed were essentially eliminated by this proceedure.
To negate the contribution of decreased proliferation in this assay, we normalized these results to the proliferation changes observed on day 2.
Comparing the contribution of cell proliferation and islet-like clusters to the total increase in insulin-positive cells suggests a hitherto uncharacterized large non-proliferative contribution.
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