Sentence examples for contributing to transformation from inspiring English sources
It is worth noting that many of the EEF1A2-mediated changes that we have described as possibly contributing to transformation are affected at the transcriptional level and represent non-canonical functions of the protein.
When plated in soft agar, SMDF but not GFP infected NSLT formed colonies in suspension with a similar efficiency to Ras infected NSLT indicating that SMDF is contributing to transformation directly and not through additional mutation (Figure 1C).
Therefore, we speculate that one potential effector mechanism of HES5 silencing could be de-repression of HES6 that in turn enhances AR regulation of key oncogenic targets, contributing to transformation and/or priming cells for subsequent acquisition of aggressive phenotypes.
The recent evidence that metabolic alteration might contribute to transformation and tumour progression raised interest in anticancer approaches aimed at controlling transformation and metastasization processes6,12,15.
These results demonstrated that transformation of CF was exclusively a biotic process, while abiotic processes contributed to transformation of CT and CFC-11.
Therefore, loss of Dnase1 and increased MMP activities are identified as factors that may contribute to transformation of mild mesangial into severe membrano-proliferative lupus nephritis.
Our studies of mouse PCT suggest that heightened expression of EEF1A2 might contribute to transformation by promoting cell cycle progression and inhibiting apoptosis.
