Sentence examples for contributing to target from inspiring English sources

Thus, our data do not support the notion of TiA contributing to target cell resistance in the murine system.

Overall, these studies show that important information on the mechanisms contributing to target organ colonization can be drawn from self-seeding or cross-seeding experimental models.

It is believed that the amphipathic nature of LfcinB allows interaction with the abundant negative charges present in cancer cells, thus contributing to target selectivity [ 34, 44].

To investigate the potential mechanism that recruits HepG2 cell death following PDT, we next set out to decipher the effect of PDT in contributing to target cell apoptosis by looking for DNA fragmentation and annexin V-fluorescein isothiocyanate (FITC)/propidium iodide (PI -stained cells using flow cytometry.

5' end sequences are critical for miRNA function [2], [41], [71] [73] and the seed region is thought to contribute to target recognition by perfect (or near perfect) complementary binding to the mRNA target site.

Base-pairing elsewhere in the miRNA, including at a so-called T1A site extending the seed region [3] and in the 3' region [3], [4], has also been variously proposed to contribute to target binding.

Together, these observations suggest that cytokines, particularly IFN-alpha, may contribute to target organ damage.

Furthermore, beyond seed site pairing, the centre and the 3′end of the miRNA sequence can contribute to target recognition.

The project aims to contribute to target 17 of the Millennium Development Goals: 'in cooperation with pharmaceutical companies, [to] provide access to affordable, essential drugs in developing countries'.

This would in turn suggest that they contribute to target specificity, as their sequences are different from the canonical miRNAs from the same pre-miRNAs.

The greater space filling function of the naphthyl group, in the context of the other interactions such as the canonical hydrogen bonding with the hinge region, contributes to target affinity and selectivity.