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For example, in the presence of both mutants, CHIP H260Q may block access of endogenous CHIP to its binding site on HIF-1α, thus contributing to stabilize the transcription factor.
Moreover, there are positive circuits that are contributing to stabilize specific attractors but not another.
On the other hand, the catalytic W164 environment in VP1 is less acidic than the corresponding region in P. chrysosporium LiP, the latter probably contributing to stabilize the VA cation radical [ 40].
However, not all positive circuits in the network are involved in network multistability; those whose participating genes cannot be in a coherent stable state according to the connectivity of the circuit (i.e., mismatch between the logical rules and the expression pattern) are not contributing to stabilize the network because they are not stable by themselves.
The interscapular region is characterized by several layers of muscles held together by a complex myofascial system, often infiltrated and covered by adipose tissue, which allows their mutual movement, contributing to stabilize the scapula against external forces and preventing its displacement or rotation [ 1, 2].
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By contrast, the Health Transition Fund managed to pool resources together, for the first time on that scale, against national sectoral targets, thus contributing to stabilizing the sector and, according to recent outcome and impact level data, may have contributed to significant progress on the health-related MDGs.
Therefore, PRMT5 and PRMT4 are likely to regulate pre-mRNA splicing, at least in part, by contributing to stabilizing weak RNA-RNA interactions between donor splice sites that deviate from the consensus sequence, and the sequence present in the U1 SnRNA that is complementary to the consensus donor splice-site sequence.
This contributes to stabilize the aggregator's profits.
In the island operation, the BESS contributes to stabilize the frequency.
In this case the steric factor of the drug molecule will contribute to stabilize the particle in colloid.
The negatively charged oxygen donors in terminal carboxyl groups can mainly contribute to stabilize the metal complex.
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CEO of Professional Science Editing for Scientists @ prosciediting.com