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Regulators frequently contributing to regulation of GEIs comprise the two-component response regulator family, AraC family, alternative sigma factors and histone-like proteins.
Our data suggest that ACE2 is a functional component of the renin-angiotensin system, metabolizing Ang II and thereby contributing to regulation of blood pressure.
PGE2, in addition of being involved in all processes leading to the classic signs of inflammation (redness, swelling, and pain); it is also known to play a key role in the pathogenesis of cardiovascular diseases, contributing to regulation of blood pressure.
Intriguingly, a recent study has demonstrated that the cytoplasmic p35 isoform of OBF1 interacts with the tyrosine kinase Syk, thus contributing to regulation of preBCR signaling and preB cell proliferation [25].
These changes in cell cycle markers induced by siRNA VRK1 are consistent with the induction of an early block in the G1 phase of the cell cycle; these results are also similar, although mechanistically different, to those induced by serum deprivation in this cell line, and therefore consistent with a role of VRK1 in contributing to regulation of cell cycle progression.
RNA splicing generates the long variant GlyR α3L185L, which is preponderantly expressed in the hippocampus and operates at presynaptic sites by contributing to regulation of neurotransmitter release.
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Multiple dimensions of epigenetic control contribute to regulation of gene expression that governs bone biology and pathology.
Surfactant proteins (SPs) and toll-like receptors (TLRs) contribute to regulation of sepsis-induced acute lung injury.
The complement system in mammals contributes to regulation of different functions including homeostasis maintenance, and support of liver, bone, and muscle regeneration57.
Sanchez, E. et al. Tanycyte pyroglutamyl peptidase II contributes to regulation of the hypothalamic-pituitary-thyroid axis through glial-axonal associations in the median eminence.
We have detected changes in several of these adhesion receptors and their intracellular mediators that also contribute to regulation of metastasis.
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