Sentence examples for contributing to potency from inspiring English sources

The possible relevance of these results in contributing to potency of phage lysins is discussed.

However, occupation of this site clearly strongly contributes to potency.

The S3 binding pocket is also well-defined, whereas the S4 pocket is very large and can tolerate a range of capping groups that are likely to contribute to potency by picking up further hydrophobic interactions.

Lastly, enzyme and ligand features contributing to the potency and selectivity differences are analysed by molecular docking.

2) The design of siRNA-encoding libraries precludes mismatches in the RNA duplex, a factor contributing to the potency of endogenous miRNAs.

In addition to the advantages described in the introduction, we have demonstrated herein the importance of mismatches in contributing to the potency of RNA duplexes; the design of the siRNA library precludes mismatches because the siRNAs are encoded by opposing DNA strands and thus are eliminated in E. coli during cloning.

An X-ray crystallography study of NDM-1/B6 complex structure is currently ongoing to investigate the key interactions contributing to the potency.

However, due to the absence of an experimental ATR structure, the determinants contributing to ATR inhibitors' potency and specificity are not well understood.

The crystal structure of this derivative reveals features contributing to its increased potency.

Thus, both these phenothiazine derivatives (4 and 5) associate with the E-helix, contributing to their inhibitor potency.

Thus, we have demonstrated that 17-AAG-dependent inhibition of NF-κB activity is tightly associated with transcriptional repression of Survivin and cIAP1 anti-apoptotic genes, thus decisively contributing to the cytotoxic potency of 17-AAG by decreasing the required "apoptotic threshold" in bladder cancer cells [ 38].