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Hyperchloremia has been shown to be negatively associated with mortality or kidney failure in certain subgroups of patients [1 3], although it is difficult to prove that it is an independent factor contributing to outcome rather than a mere marker of specific conditions or severity of illness [4, 5].
Additional studies to identify other modifiable risk factors contributing to outcome differences between immigrant populations are also warranted.
Bystander rescue breathing was the most significant factor contributing to outcome; additionally, two other factors eye-witness to arrest and age—were also signifactors eye-witness
Given the sample size, the heterogeneity of the clinical picture and the number of other factors likely contributing to outcome, this is not surprising.
Findings from this international collaboration generated using extensive data will provide strong and novel evidence regarding practices contributing to outcome variation with broad relevance to NICUs within iNeo and worldwide.
To identify factors contributing to outcome variation between networks, detailed information will be obtained on health service provision, including units' physical layout, environmental characteristics, human factors, and management practices at the national and site level.
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Unmeasured characteristics may have contributed to outcome differences.
Anatomical reduction and rigid internal fixation are the two important surgeon controlled factors that may contribute to outcome.
As recently discussed, another major issue is represented by the variability of methodology (needle positioning, treatment duration, session frequency), which contributes to outcome variability [122].
Genetic factors might be postulated to contribute to outcome, and indeed to causation of MTLE + HS.
Additionally, host response during infection is likely to contribute to outcome.
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