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This causes an overpruning of the synapses, occurring in early stage Alzheimer's disease and contributing to memory loss.
Analysis of the molecular mechanisms underlying the generation and maintenance of central sensitization and LTP indicates that, although there are differences between the synaptic plasticity contributing to memory and pain, there are also striking similarities.
A growing body of converging evidence points to sleep as contributing to memory consolidation, in particular.
Both processes contributing to memory retrieval are associated with different neural networks [35] and are differentially susceptible to aging-related changes.
This relationship, (asymmetric window of Hebb rule < theta cycle < duration of theta phase precession), is important to generate theta phase precession contributing to memory formation, and the small fluctuation of these parameters is not critical.
Thus, the dnc sensitive delayed secondary Ca2+ response occurring specifically in the MB lobes may play a critical role in cellular processes (synaptic transmission and/or synaptic plasticity) contributing to memory formation.
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The fornix, which also contributes to memory function, had atrophied.
Sleep quantity, however, appears to uniquely contribute to memory performance.
Alcohol: Having more than the recommended number of daily drinks can contribute to memory loss.
Sleep spindles are thought to induce synaptic changes and thereby contribute to memory consolidation during sleep.
Exactly how each of these hippocampal sub-regions contribute to memory formation, storage, and retrieval is still not entirely clear, however.
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