Sentence examples for contributing to affinity from inspiring English sources
Domain C exhibited a preference for a positive charge over a neutral function, with the space this functional group occupies contributing to affinity.
The additional salt bridge remains strongly solvent-exposed and thus does not contribute to affinity.
Crystal structures of the QM PDZ domain both free and bound to ligands showed structural features central to binding (enthalpy), while nuclear-magnetic-resonance-based methyl relaxation experiments and isothermal titration calorimetry revealed that conformational entropy contributes to affinity.
(1) Since the linker positions range from highly conserved to semi-conserved to nonconserved and contribute to affinity, selectivity, and allosteric response, we assert that sequence/function analyses must identify positions in the LacI/GalR linkers to be qualified as "successful".
Poxels with some probability of being populated were not clustered, indicating that several sites in the large cavity contribute to affinity.
We can, in fact, show that the catalytic domain of RapGAP is much less active than the full-length protein, as it contributes to affinity.
Given that the remaining peptide residues contribute to affinity through both backbone and sidechain interactions, it is unclear to what extent mutations at these positions would affect affinity or modulate enzyme Km values.
In this context, we agree that dissection of residues that contribute to affinity differences using mutagenesis and cosedimentation assays is an interesting future direction but feel that this is beyond the scope of the current study.
These results suggest that it is its metallic nature contributing to the affinity of QD for actin microfilaments, which in turn favors a complexation reaction or precipitation.
Development of resistance thus appears to be associated with a change of the distinctive kinetic parameter contributing to high affinity.
Kinetic and thermodynamic experiments validate the structural findings and implicate the C-terminal residues of Cdk9 in contributing to the affinity for DRB.
