Sentence examples for contributing to a switch from inspiring English sources

It is plausible that in the event of chronic damage or stress, DBC1 plays a role in checkpoint control, contributing to a switch in cell fate and promoting cellular senescence.

An interesting possibility is that Dom functions at both inactive and active E2F target promoters, potentially contributing to a switch between negative and positive regulation of transcription and cell division.

It was also assumed that the maintenance of ATP stores might contribute to a switch of cell death from necrosis to apoptosis, as apoptosis has been associated with higher ATP content compared to necrotic cell death.

Here we show that the gastric environment can contribute to a switch in Lewis phenotype in the two experimental mouse models.

Such genetic and epigenetic events may contribute to a switch from a normal developmental program in adult cells during the formation of diseased tissues, including cancers.

Persistent EGFR signaling, coupled with the autocrine induction of membrane-bound HRG, contributed to a switch in the regulation of cell survival from HER2-HER3-PI3K in treatment-naïve HER2+ breast cancer cells to an HRG-driven EGFR-HER3-PI3K-PDK1 sinnaling axis in lapatinib-resistant tumor cells.

Model predictions indicate that the transition from high to low runoff coefficients in the Blue River basin is linked to variations of water table depth and surface soil moisture, contributing to a seasonal switching of surface runoff generation mechanisms, from saturation excess to infiltration excess.

These data established the core position of p53 in transducing the p38 signal to downstream cascades, including eIF2 α and eIF4E, and eventually contributing to a selenite-driven switch from autophagy to apoptosis.

These data demonstrate that increasing amount of NMDA activated more receptors, which contribute to a program switch from survival to cell death.

Our analysis demonstrates that two independent positive feedback loops in the Bcl-2 network contribute to an inherent switch to govern apoptosis decision.

This may contribute to an adequate switch between fatty acid and glucose substrate use under postprandial conditions and is of importance for the maintenance of normal glucose tolerance.