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Each primary study will be examined for evidence based on how it supports, refutes, reinterprets or refocuses the novice theories developed in the first step, looking at how each study contributes to refining the initial theory.
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RM, KH and BN were primarily responsible for developing the first drafts of the manuscript; KH, KM and CR made a major contribution to the analysis; ED, UD and PV contributed to refining the concepts and content comprising the final manuscript.
The remaining authors contributed to refining the ideas and to writing this paper.
Our results clarify a previously reported paradoxical result in protein nanomechanics and contribute to refining our toolbox for understanding the unfolding mechanism used by translocases and degradation machines.
"Our participation in the MITEF competition has greatly contributed to refining the final product to be presented to potential customers, clarifying and justifying the product price and elaborating some first approaches with regards to the international market". —Eleftheria Mamidaki of Help & Win.
Group S amplification likely contributed to refining the regulatory circuit controlling the organism's energy status.
However, the changes in ribosome profiles and rRNA structures in multiple mutants suggest the intriguing possibility that they may each contribute to refining the structure and function of the translational apparatus.
MZ and DK contributed to refining the study design.
All co-authors contributed to refining the analyses, interpreting the results, and improving the manuscript.
Imaging research will contribute to refining the assessment of pain in infants and potentially may guide clinical practice.
RAN is responsible for the day to day co-ordination of the trial, has contributed to refining the protocol and outcome measure package.
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