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Even if clinical guidelines exist, disagreement among clinicians regarding the strength of the underlying data, and other factors, contributes to incomplete guideline compliance.
Moreover, as shown in the following section, incomplete deployment probably contributes to incomplete protection even when microbicide agents are delivered at concentrations much higher than needed to inactivate pathogens in vitro.
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This may have contributed to incomplete adoption of the primary stages of the WHO detection protocol, alongside pragmatic or logistical issues associated with study design.
Such TFs prefer 5-TAA/TTA-3 elements (overrepresented in promoters of psoriasis-decreased DEGs), and their decreased expression in psoriasis may contribute to incomplete KC differentiation, thereby favoring KC proliferation [83,84].
Late first ANC registration has been found to contribute to incomplete IPTp [ 16, 29, 30].
Defects in the aging lysosomal compartment may also contribute to incomplete digestion of glycogen.
Hyperglycemia in STEMI patients has direct acute negative cardiovascular effects contributing to incomplete myocardial reperfusion and CMF impairment [ 24- 28].
Redox imbalance under certain conditions and in engineered strains may contribute to incomplete substrate utilization and may direct fermentation products to undesirable overflow metabolites.
A combination of slow axonal regeneration, structural changes in muscle targets, and an increasingly less supportive stromal environment for regeneration all contribute to incomplete functional recovery.
An additional factor contributing to incomplete suppression is likely to be the fact that our hyperpolarizing reagent is unable to mimic endogenous temporal variations in Vmem of healthy cells.
Finally, CD28 expression (delivering a positive co-signal after ligation to B7.1 or B7.2) was depressed in trauma patients' anergic T cells and may contribute to incomplete activation of these cells [ 36].
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