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Over diagnosis of malaria contributes to improper treatment, wastage of drugs and resistance to the few available drugs.
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Lack of physical strength by caretakers may contribute to improper installation of child restraints.
Besides, the considerable progress made in understanding the biological and molecular basis of cancer during the past 50 years has not been translated into a notable improvement of its incidence and mortality (Kiberstis and Travis 2006), neither in the control of treatment-limiting side effects, also contributing to improper treatment compliance (Frenkel 2013).
These changes could contribute to improper function of the FRT later in life that manifests as an infertility phenotype.
The osseous deformity in Ranawat type-II valgus deformity may influence the accuracy of conventional instrumentation and contribute to improper bone cuts [ 14– 14].
Studies in murine models of burn injury indicate that higher estrogen levels in female mice contribute to improper cell-mediated immune response to injury with an aberrant inflammatory response that increases mortality.
The exon 11 region of E-cadherin was also analyzed by the ChIP assay to determine whether there are any specific epigenetic alterations that contribute to improper splicing of this exon.
Poor personnel training increases the risk of a LAI or other biological accident in the laboratory, and may also contribute to improper pathogen accounting, storage and transportation, which in turn could contribute to the illicit acquisition of biological agents by terrorists or would-be bio-criminals.
Furthermore, the osseous deformity in Ranawat type-II valgus deformity (including hypoplasia of the distal femur, rotational deformity of the tibia and femur, unusual proximal femoral neck-shaft angles, and maltracking of the patella) may influence the accuracy of conventional instrumentation and contribute to improper bone cuts.
It is possible that inappropriate regulation of pathways controlling cytokinesis caused by decreased Chk1 levels might contribute to the improper enucleation of the erythroid cells.
Therefore, missense mutations in the Ubl domain could contribute to its improper folding, instability that would interfere with the overall structure of parkin or compromise its interactions with other proteins.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com