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Although the role of cytoplasmic tail region of TSHR is not known very well, our data support the concepts that the cytoplasmic tail play a role in signal transduction and that Ile691 contributes in keeping TSHR inactive in both the Gαs/cAMP and the Gαq/11/IP pathways.
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Although the continuous exposure in our study should not have increased the mice's body temperatures, it may have contributed in keeping the animal's body temperature above ambient, therewith economizing mitochondrial heat production.
"As a government, it is essential that we stop violence in schools and wipe out age-old factors such as 'illegal school charges', 'ghost schools' and 'ghost teachers' that have contributed in keeping our children out of school", said Hon Dr Minkailu Bah, Minister of Education, Youths and Sports.
A team leader has to work hard to contribute in keeping the team morale high.
For individuals, this sense of solidarity implies not simply that the individual receives benefits from these institutions, but that she also contributes back in keeping with a value of reciprocity.
His past criticism of outside groups, some Democrats said, had made it hard to persuade donors to back Priorities USA Action, contributing to its problems in keeping up with conservative groups.
The National Institute of Standards and Technology also hopes to contribute $5 million in 2013, in keeping with its mission to set industry standards for advanced manufacturing technologies.
The National Institute of Standards and Technology also hopes to contribute $5 million in 2013, in keeping with its mission to help develop industry standards for advanced manufacturing technologies.
They suggested that the test of time contributes to a simple heuristic in keeping with Bayes theorem.
The federal and provincial government contributed up to $50 million of that, in keeping with their agreement to match private investment.
This suggests that copper may contribute to ROS-dependent kinling in macrophages, in keeping with the well-known capacity of Cu(I) to catalyse the generation of hydroxyl radical from H2O2.
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