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The trust management becomes more complex when the observing node (called recommender) itself behaves untrustworthy, which contributes false evidences.
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This caveat is due to highly expressed transcripts contributing false positive duplicate reads due to random sampling of read start locations along the transcript.
Sequencing error and misalignment can also contribute false mutation-supporting reads to the normal.
We concluded that our low stringency bovine set captured a majority of actual bidirectional promoters, but that limited annotations contributed false positive and false negative predictions.
Moreover, dead cells can contribute false positive signals severely because BMVC can enter the nucleus of dead cells and show strong fluorescence 19.
While true positive peptide assignments concentrate over a small subset of the protein database, false positive peptide assignments distribute broadly over the protein database and therefore mostly contribute false positive peptide discoveries.
This removes all reads that do not contain unique sequence between the samples, thus removing reads that do not represent variation between the sample but may contribute false positives due to mapping errors.
This dissociation indicates that elaborative perceptual processing, but not basic sensory processing, contributes to false remembering.
Cells co-expressing NlpΔ8 mutant (with all eight plk1 phospho-sites mutated to alanine) and Plk1 T210D are tremendously resistant to fragmentation of centrosomal Nlp into cytoplasm, which in turn contributes to false spindle formation.
Such differences may contribute to false-positive or false-negative observations and need to be factored into any overall characterization.
Several other conditions can contribute to false-positive or false-negative IHC results, including tissue processing, reagent variability, antigen retrieval methods, scoring interpretation, tumor heterogeneity, and the semiquantitative nature of the test [ 7- 12].
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