This paper proposes a bio-constrained system-level model that contributes a major step towards this integration.
The aim of this special issue is to contribute with a step-forward filling in the aforementioned gaps.
In addition, this protective role could be contributed to "taking a step back" from a problematic situation by favouring an emotional recovery.
A more likely explanation for the earlier observation that E113A and E117A can restore the replication defect of 173GG is that these residues are contributing to pgRNA encapsidation, a step for which the net charge of the capsid lumen does appear to be important [21], [29], [37].
Researchers interested in studying the genetic regulation of particular processes or traits must first identify the genes contributing to the phenotype, a step which can be particularly challenging in organisms for which genomic data are not yet available.
Together, these findings demonstrate that B5 contributes to HSV infection at a step downstream of viral entry and nuclear transport.
That should make unsurprising Larry's steadfast support for a big stimulus package in 2009, a step that contributed mightily to the economic recovery.
The Pentagon has been pressing allies to contribute forces to bolster security, a step that would ease the burden on American soldiers and give the occupation a more international face.
However, it is at present unclear how this residue contributed so substantially to such a step, because T81 is located on the protein surface and far away from the active site and access tunnels (Figure 2) (Okai et al. [2013]).
Such a step would contribute to slowing climate change because forests store between one-third and one-fourth of global carbon dioxide (CO2) emissions, and tropical forests alone absorb almost one-fifth of all carbon dioxide released each year from the burning of fossil fuels.
