Hence, the "controls" were patients who did not receive alteplase in neuroprotection trials but received either placebo or a neuroprotective drug as per the randomisation protocol for each contributing trial.
We call on others to join us, to contribute trial documents they have obtained from public sources that need publishing or republishing, and to help us with the writing.
This is not straightforward in practice: reviewers must decide how to handle missing outcome data in the contributing trials.
Values of EC50 and the Hill coefficient (see next section) are assumed identical in the contributing trials or between populations.
As the contributing trials spanned 30 years, the types of chemotherapy used varied considerably and consequently the pre-specified main analysis sub-divided trials into chemotherapy categories.
R.B.J. contributed to trial design, and led trial conduct and manuscript preparation.
The absence of clear communication between trial participants and trial investigators contributed to premature trial closures in at least two sites [ 1, 2].
MD contributed to trial design and protocol development, had overall responsibility for conduct of the trial, and contributed to recruiting patients, deciding the statistical analysis, interpreting the data and preparing the manuscript.
An article last Friday about the money contributed by trial lawyers to Republican races in Texas misstated Steve Mostyn's title at the Texas Trial Lawyers Association.
