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These results demonstrated that transformation of CF was exclusively a biotic process, while abiotic processes contributed to transformation of CT and CFC-11.
The prostatic stroma of Tgfbr2fspKO mice independently contributed to transformation of the adjacent epithelia as well as castrate resistance.
SNM contributed to transformation protocol development.
LL constructed A. fimbriata cDNA libraries for EST sequencing and contributed to transformation protocol development.
YH performed tissue collection, RNA isolations, and contributed to transformation protocol development.
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However, it remains unclear to what extent this and other metabolic changes specifically contribute to transformation.
To test if BORIS expressed at low levels might contribute to transformation, we studied NIH3T3 cells for anchorage independent growth.
Therefore, loss of Dnase1 and increased MMP activities are identified as factors that may contribute to transformation of mild mesangial into severe membrano-proliferative lupus nephritis.
Our studies of mouse PCT suggest that heightened expression of EEF1A2 might contribute to transformation by promoting cell cycle progression and inhibiting apoptosis.
When plated in soft agar, SMDF but not GFP infected NSLT formed colonies in suspension with a similar efficiency to Ras infected NSLT indicating that SMDF is contributing to transformation directly and not through additional mutation (Figure 1C).
It is worth noting that many of the EEF1A2-mediated changes that we have described as possibly contributing to transformation are affected at the transcriptional level and represent non-canonical functions of the protein.
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